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Yale Neuroimaging in PTSD Study 

This study consists of four MRI scan; MRI stands for Magnetic Resonance Imaging. This is a technique that uses radio waves and a strong magnetic field to look at oxygen levels in the brain. The more active a certain part of the brain is, the more oxygen it will require to function. This scan helps us see, in real time which parts of the brain are the most activated.

MRI Scans do not use any needles or radiation. We do, however, use closed MRI scanners, which some people may feel claustrophobia inducing. Please take this into account when considering participating in this study.

MRI Scans

About the Study

This observational study uses magnetic resonance imaging (MRI) to look at the brains of people receiving evidence-based therapies (therapy is not offered through the study).


We look for neural activity that has been associated with PTSD symptoms--particularly parts of the brain which relate to fear and memory.


Changes in the brain will be measured at 4 MR imaging appointment​s, which will be spaced out across the course of a year (baseline, 3 month, 6 month, 12 month).


Our aim is to better understand how ​PTSD treatment affects the brain and how a reduction in symptoms may present itself in one's neurocircuitry .

Screening Procedure


1. Fill out our pre-screen survey. 

2. If you screen in, you will be directed to fill out a contact form. We will then get in touch with you for a short (5-15 minute) over-the-phone conversation, where we will ask you some questions and give you more details about our research.

3. Should you remain interested and eligible, we will bring you in for an in-person screening appointment. This visit includes an interview with a clinician to discuss your psychiatric health. You will also be asked to complete several questionnaires.

HIC # 2000025892

If you have PTSD and are ​receiving a psychotherapy ​or drug treatment, you may be eligible for this study!

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