Neuroimaging PTSD

Yale Neuroimaging PTSD Subtypes Study

This study consists of one MRI scan; MRI stands for Magnetic Resonance Imaging. This is a technique that uses radio waves and a strong magnetic field to look at oxygen levels in the brain. The more active a certain part of the brain is, the more oxygen it will require to function. This scan helps us see, in real time which parts of the brain are the most activated.

MRI Scans do not use any needles or radiation. We do, however, use closed MRI scanners, which some people may feel claustrophobia inducing. Please take this into account when considering participating in this study.

Our brains are made up of vast interconnected networks of cells called neurons. Essentially, different parts of the brain "talk" to one another through these connections. All of our memories, habits, and thought patterns rely on communication through neural networks.

Neural networks can be modified. They can change with experiences, age, and learning new things. We can work to change our neural networks to stop bad habits, negative thoughts, or unwanted memories.

This study consists of one MEG scan; MEG stands for magnetoencephalography. This is a non-invasive technique that measures the magnetic fields generated by the brain's electrical activity. MEG is a direct measure of brain functioning, and its fields pass through the head without any form of distortion which gives rise to its high temporal and spatial resolution.

MEG does not contain any needles or radiation. The machine, itself, is set up more like a chair, so you will be sitting for the duration of the study looking at the tasks in front of you. The machine resembles a large helmet, as only your head is inside the machine from your eyebrows and up.

About the Study

This observational study uses magnetic resonance imaging (MRI) and magnetoencephalography (MEG) to observe how the brain reacts to positive, neutral, and negative stimuli. (therapy is not offered through the study).

We look for neural activity that has been associated with PTSD symptoms--particularly parts of the brain which relate to fear and memory.

There are two imaging sessions for this study. Both the MRI and MEG are conducted on the same day, with both scans being around two hours long.

Our aim is to better understand how PTSD symptoms are related to neurocircuitry.

There is the potential to earn up to $300 for this study over the course of three appointments.

Screening Procedure

1. Fill out our pre-screen survey.

2. If you screen in, you will be directed to fill out a contact form. We will then get in touch with you for a short (15-30 minute) over-the-phone conversation, where we will ask you some questions and give you more details about our research.

3. Should you remain interested and eligible, we will bring you in for an in-person screening appointment. This visit includes an interview with a clinician to discuss your psychiatric health. You will also be asked to complete several questionnaires.

HIC # 2000025892

If you have PTSD you may be eligible for this study!

Take Our Screening Survey